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HBV Target gene Detail Information

> AKAP9 Gene Search Result


Gene Information
Gene Name AKAP9
Gene ID 10142
Gene Full Name A-kinase anchoring protein 9
Gene Alias LQT11; PRKA9; AKAP-9; CG-NAP; YOTIAO; AKAP350; AKAP450; PPP1R45; HYPERION; MU-RMS-40.16A
Transcripts ENSG00000127914
Virus HBV
Gene Type protein coding
HPA Location Info Golgi apparatus;Centrosome;Vesicles;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Gene Function Oncogene
Uniport_ID Q99996
HGNC ID HGNC:379
VEGA ID OTTHUMG00000131127
OMIM ID 604001
String ID 9606.ENSP00000348573
PharmGKB ID PA24673
Target gene [AKAP9] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002129 chr7 110 209 17 336 View
1002370 chr7 108 167 11 286 View
1002447 chr7 107 155 9 271 View
1002455 chr7 108 154 9 271 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of AKAP9 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
AKAP9 expression: Low -> High
Lollipop of AKAP9 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of AKAP9 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of AKAP9 expression and immune infiltrating cell level correlation result in HBV+ samples
AKAP9 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).