HBV Target gene Detail Information

> AKAP6 Gene Search Result


Gene Information
Gene Name AKAP6
Gene ID 9472
Gene Full Name A-kinase anchoring protein 6
Gene Alias ADAP6; PRKA6; mAKAP; ADAP100; AKAP100
Transcripts ENSG00000151320
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q13023
HGNC ID HGNC:376
VEGA ID OTTHUMG00000140207
OMIM ID 604691
String ID 9606.ENSP00000280979
PharmGKB ID PA24670
Target gene [AKAP6] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1001776 chr14 8 9 471 488 View
1012021 chr14 3 5 8 View
1017499 chr14 1 1 View
1018798 chr14 0 View
1019138 chr14 0 View
1019286 chr14 0 View
1019953 chr14 0 View
1400480 chr14 8 7 15 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of AKAP6 expression and immune infiltrating cell level correlation result in HBV+ samples
AKAP6 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).