HTLV1 Target gene Detail Information

> AKAP3 Gene Search Result


Gene Information
Gene Name AKAP3
Gene ID 10566
Gene Full Name A-kinase anchoring protein 3
Gene Alias CT82; SOB1; FSP95; PRKA3; HEL159; AKAP110; AKAP 110
Transcripts ENSG00000111254
Virus HTLV1
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID O75969
HGNC ID HGNC:373
VEGA ID OTTHUMG00000168226
OMIM ID 604689
String ID 9606.ENSP00000228850
PharmGKB ID PA24667
Target gene [AKAP3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6013393 chr12 19 19 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of AKAP3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
AKAP3 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of AKAP3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
AKAP3 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of AKAP3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
AKAP3 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).