HBV Target gene Detail Information

> AKAP13 Gene Search Result


Gene Information
Gene Name AKAP13
Gene ID 11214
Gene Full Name A-kinase anchoring protein 13
Gene Alias BRX; LBC; p47; HA-3; Ht31; c-lbc; PRKA13; AKAP-13; AKAP-Lbc; ARHGEF13; PROTO-LB; PROTO-LBC
Transcripts ENSG00000170776
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Gene Function Oncogene
Uniport_ID Q12802
HGNC ID HGNC:371
VEGA ID OTTHUMG00000172205
OMIM ID 604686
String ID 9606.ENSP00000354718
PharmGKB ID PA24665
Target gene [AKAP13] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1007192 chr15 25 3 1 29 View
1007193 chr15 25 3 1 29 View
1008338 chr15 13 8 21 View
1011428 chr15 8 1 9 View
1011807 chr15 2 6 8 View
1400374 chr15 60 16 299 375 View
1402088 chr15 25 3 1 29 View
1402089 chr15 25 3 1 29 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of AKAP13 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
AKAP13 expression: Low -> High
Lollipop of AKAP13 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of AKAP13 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of AKAP13 expression and immune infiltrating cell level correlation result in HBV+ samples
AKAP13 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).