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HIV Target gene Detail Information

> AIFM1 Gene Search Result


Gene Information
Gene Name AIFM1
Gene ID 9131
Gene Full Name apoptosis inducing factor mitochondria associated 1
Gene Alias AIF; CMT2D; CMTX4; COWCK; DFNX5; NADMR; NAMSD; PDCD8; COXPD6
Transcripts ENSG00000156709
Virus HIV
Gene Type protein coding
HPA Location Info Mitochondria;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID O95831
HGNC ID HGNC:8768
VEGA ID OTTHUMG00000022392
OMIM ID 300169
String ID 9606.ENSP00000287295
Drugbank ID BE0000965
PharmGKB ID PA162376129
Target gene [AIFM1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4002233 chrX 104 104 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of AIFM1 expression and immune infiltrating cell level correlation result in HIV+ samples
AIFM1 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of AIFM1 expression and immune infiltrating cell level correlation result in HIV+ samples
AIFM1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).