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HBV Target gene Detail Information

> AHRR Gene Search Result


Gene Information
Gene Name AHRR
Gene ID 57491
Gene Full Name aryl-hydrocarbon receptor repressor
Gene Alias AHH; AHHR; bHLHe77
Transcripts ENSG00000063438
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Gene Function Suppressor gene
Uniport_ID A9YTQ3
HGNC ID HGNC:346
VEGA ID OTTHUMG00000162171
OMIM ID 606517
String ID 9606.ENSP00000323816
PharmGKB ID PA24639
Target gene [AHRR] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000839 chr5 918 318 120 1356 View
1002097 chr5 329 16 1 346 View
1004607 chr5 68 6 1 75 View
1005283 chr5 56 1 57 View
1005284 chr5 56 1 57 View
1005597 chr5 49 2 51 View
1007184 chr5 22 6 1 29 View
1010682 chr5 6 5 11 View
1011368 chr5 6 3 9 View
1012075 chr5 3 4 7 View
1403329 chr5 3 4 7 View
1403746 chr5 22 6 1 29 View
1403747 chr5 329 16 1 346 View
1403748 chr5 68 6 1 75 View
1403913 chr5 918 318 120 1356 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of AHRR expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
AHRR expression: Low -> High
Lollipop of AHRR expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of AHRR expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of AHRR expression and immune infiltrating cell level correlation result in HBV+ samples
AHRR expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).