HIV Target gene Detail Information

> AHR Gene Search Result

Gene Information

Gene Name	AHR
Gene ID	196
Gene Full Name	aryl hydrocarbon receptor
Gene Alias	bHLHe76
Transcripts	ENSG00000106546
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Predicted intracellular proteins, Transcription factors
Gene Function	Suppressor gene
Uniport_ID	P35869
HGNC ID	HGNC:348
VEGA ID	OTTHUMG00000149967
OMIM ID	600253
String ID	9606.ENSP00000242057
Drugbank ID	BE0003721
PharmGKB ID	PA24641

Target gene [AHR] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001159	chr7	16	96	91	203	View
4001597	chr7	112	15	21	148	View
4014526	chr7	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of AHR expression and immune infiltrating cell level correlation result in HIV+ samples
AHR expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of AHR expression and immune infiltrating cell level correlation result in HIV+ samples
AHR expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).