HBV Target gene Detail Information

> AGTR1 Gene Search Result


Gene Information
Gene Name AGTR1
Gene ID 185
Gene Full Name angiotensin II receptor type 1
Gene Alias AT1; AG2S; AT1B; AT1R; AT1AR; AT1BR; AT2R1; HAT1R; AGTR1B
Transcripts ENSG00000144891
Virus HBV
Gene Type protein coding
HPA Location Info Vesicles;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters
Gene Function Suppressor gene
Uniport_ID P30556
HGNC ID HGNC:336
VEGA ID OTTHUMG00000159503
OMIM ID 106165
String ID 9606.ENSP00000419422
Drugbank ID BE0000062
PharmGKB ID PA43
Target gene [AGTR1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005887 chr3 39 4 3 46 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of AGTR1 expression and immune infiltrating cell level correlation result in HBV+ samples
AGTR1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).