HIV Target gene Detail Information

> AGO4 Gene Search Result

Gene Information

Gene Name	AGO4
Gene ID	192670
Gene Full Name	argonaute 4, RISC catalytic component
Gene Alias	EIF2C4
Transcripts	ENSG00000134698
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytoplasmic bodies;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9HCK5
HGNC ID	HGNC:18424
VEGA ID	OTTHUMG00000004243
OMIM ID	607356
String ID	9606.ENSP00000362306
PharmGKB ID	PA38330

Target gene [AGO4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005055	chr1	22	13	1	36	View
4008319	chr1	14	1		15	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of AGO4 expression and immune infiltrating cell level correlation result in HIV+ samples
AGO4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).