HIV Target gene Detail Information

> AGO3 Gene Search Result

Gene Information

Gene Name	AGO3
Gene ID	192669
Gene Full Name	argonaute 3, RISC catalytic component
Gene Alias	EIF2C3
Transcripts	ENSG00000126070
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytoplasmic bodies;Cytosol;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9H9G7
HGNC ID	HGNC:18421
VEGA ID	OTTHUMG00000184172
OMIM ID	607355
String ID	9606.ENSP00000362287
PharmGKB ID	PA38329

Target gene [AGO3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000556	chr1	254	51	68	373	View
4005056	chr1	29	6	1	36	View
4006515	chr1	8	16		24	View
4010253	chr1	5	4		9	View
4010648	chr1	7	1		8	View
4015904	chr1				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of AGO3 expression and immune infiltrating cell level correlation result in HIV+ samples
AGO3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).