HIV Target gene Detail Information

> AGFG2 Gene Search Result

Gene Information

Gene Name	AGFG2
Gene ID	3268
Gene Full Name	ArfGAP with FG repeats 2
Gene Alias	HRBL; RABR
Transcripts	ENSG00000106351
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	O95081
HGNC ID	HGNC:5177
VEGA ID	OTTHUMG00000156029
OMIM ID	604019
String ID	9606.ENSP00000300176
PharmGKB ID	PA29451

Target gene [AGFG2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004631	chr7	17	24		41	View
4005212	chr7	11	24		35	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of AGFG2 expression and immune infiltrating cell level correlation result in HIV+ samples
AGFG2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of AGFG2 expression and immune infiltrating cell level correlation result in HIV+ samples
AGFG2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).