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HIV Target gene Detail Information

> AGER Gene Search Result


Gene Information
Gene Name AGER
Gene ID 177
Gene Full Name advanced glycosylation end-product specific receptor
Gene Alias RAGE; SCARJ1
Transcripts ENSG00000230514
Virus HIV
Gene Type protein coding
HPA Location Info Cell Junctions;Plasma membrane;Nucleoli fibrillar center;Predicted to be secreted;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins
Uniport_ID Q15109
HGNC ID HGNC:320
VEGA ID OTTHUMG00000012746
OMIM ID 600214
String ID 9606.ENSP00000364210
PharmGKB ID PA24617
Target gene [AGER] related to VISs
DVIDChromosomeHMTFBSCASum of Overlapped RecordsDetail
4002922 chr6 75 75 View
Showing 1 to 1 of 1 entries
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Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of AGER expression and immune infiltrating cell level correlation result in HIV+ samples
AGER expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of AGER expression and immune infiltrating cell level correlation result in HIV+ samples
AGER expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).