HIV Target gene Detail Information

> AGBL5 Gene Search Result

Gene Information

Gene Name	AGBL5
Gene ID	60509
Gene Full Name	ATP/GTP binding protein like 5
Gene Alias	CCP5; RP75
Transcripts	ENSG00000084693
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytokinetic bridge;Cytosol;Microtubules;
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q8NDL9
HGNC ID	HGNC:26147
VEGA ID	OTTHUMG00000128406
OMIM ID	615900
String ID	9606.ENSP00000353249
PharmGKB ID	PA162375816

Target gene [AGBL5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4008081	chr2	10	6		16	View
4012156	chr2	5			5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of AGBL5 expression and immune infiltrating cell level correlation result in HIV+ samples
AGBL5 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of AGBL5 expression and immune infiltrating cell level correlation result in HIV+ samples
AGBL5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).