HPV Target gene Detail Information

> AGAP4 Gene Search Result

Gene Information

Gene Name	AGAP4
Gene ID	119016
Gene Full Name	ArfGAP with GTPase domain, ankyrin repeat and PH domain 4
Gene Alias	AGAP8; MRIP2; AGAP-4; AGAP-8; CTGLF1; CTGLF5
Transcripts	ENSG00000188234
Virus	HPV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q96P64
HGNC ID	HGNC:23459
VEGA ID	OTTHUMG00000018088
String ID	9606.ENSP00000392513
PharmGKB ID	PA164715122

Target gene [AGAP4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5003461	chr10	3			3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE140662 (GEO)	Condyloma Acuminatum	8	Condyloma acuminata (HPV+)(5), Skin(3)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662
HeatMap of cell type fractions in all samples	Lollipop of AGAP4 expression and immune infiltrating cell level correlation result in HPV+ samples
AGAP4 expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of AGAP4 expression and immune infiltrating cell level correlation result in HPV+ samples
AGAP4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).