HBV Target gene Detail Information

> AGAP2 Gene Search Result

Gene Information

Gene Name	AGAP2
Gene ID	116986
Gene Full Name	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
Gene Alias	PIKE; GGAP2; CENTG1
Transcripts	ENSG00000135439
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;Midbody ring;
HPA Protein Class Info	Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	Q99490
HGNC ID	HGNC:16921
VEGA ID	OTTHUMG00000170285
OMIM ID	605476
String ID	9606.ENSP00000449241
PharmGKB ID	PA26411

Target gene [AGAP2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001034	chr12	185	604	327	1116	View
1001050	chr12	182	598	326	1106	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of AGAP2 expression and immune infiltrating cell level correlation result in HBV+ samples
AGAP2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).