HTLV1 Target gene Detail Information

> AFTPH Gene Search Result

Gene Information

Gene Name	AFTPH
Gene ID	54812
Gene Full Name	aftiphilin
Gene Alias	Nbla10388
Transcripts	ENSG00000119844
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytosol;Golgi apparatus;Vesicles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q6ULP2
HGNC ID	HGNC:25951
VEGA ID	OTTHUMG00000129539
String ID	9606.ENSP00000238855
PharmGKB ID	PA145149871

Target gene [AFTPH] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6017550	chr2	7	3		10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of AFTPH expression and immune infiltrating cell level correlation result in HTLV1+ samples
AFTPH expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of AFTPH expression and immune infiltrating cell level correlation result in HTLV1+ samples
AFTPH expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of AFTPH expression and immune infiltrating cell level correlation result in HTLV1+ samples
AFTPH expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).