HBV Target gene Detail Information

> AFF4 Gene Search Result

Gene Information

Gene Name	AFF4
Gene ID	27125
Gene Full Name	AF4/FMR2 family member 4
Gene Alias	MCEF; CHOPS; AF5Q31
Transcripts	ENSG00000072364
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoli fibrillar center;Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Predicted intracellular proteins
Uniport_ID	Q9UHB7
HGNC ID	HGNC:17869
VEGA ID	OTTHUMG00000059838
OMIM ID	604417
String ID	9606.ENSP00000265343
PharmGKB ID	PA142672641

Target gene [AFF4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1013334	chr5	1	4		5	View
1015682	chr5		2		2	View
1015683	chr5		2		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of AFF4 expression and immune infiltrating cell level correlation result in HBV+ samples
AFF4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).