HBV Target gene Detail Information

> AFF4 Gene Search Result


Gene Information
Gene Name AFF4
Gene ID 27125
Gene Full Name AF4/FMR2 family member 4
Gene Alias MCEF; CHOPS; AF5Q31
Transcripts ENSG00000072364
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoli fibrillar center;Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Disease related genes, Predicted intracellular proteins
Uniport_ID Q9UHB7
HGNC ID HGNC:17869
VEGA ID OTTHUMG00000059838
OMIM ID 604417
String ID 9606.ENSP00000265343
PharmGKB ID PA142672641
Target gene [AFF4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1013334 chr5 1 4 5 View
1015682 chr5 2 2 View
1015683 chr5 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of AFF4 expression and immune infiltrating cell level correlation result in HBV+ samples
AFF4 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).