HBV Target gene Detail Information

> AFF3 Gene Search Result

Gene Information

Gene Name	AFF3
Gene ID	3899
Gene Full Name	AF4/FMR2 family member 3
Gene Alias	LAF4; MLLT2-like
Transcripts	ENSG00000144218
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Cancer-related genes, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	P51826
HGNC ID	HGNC:6473
VEGA ID	OTTHUMG00000153011
OMIM ID	601464
String ID	9606.ENSP00000386834
PharmGKB ID	PA30264

Target gene [AFF3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1007300	chr2	27	1		28	View
1009137	chr2	14	3		17	View
1009771	chr2	13	1		14	View
1013573	chr2	2	3		5	View
1016144	chr2	1		1	2	View
1017704	chr2				0	View
1017705	chr2				0	View
1019803	chr2				0	View
1019960	chr2				0	View
1403453	chr2				0	View
1403454	chr2				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of AFF3 expression and immune infiltrating cell level correlation result in HBV+ samples
AFF3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).