HBV Target gene Detail Information

> AFAP1 Gene Search Result

Gene Information

Gene Name	AFAP1
Gene ID	60312
Gene Full Name	actin filament associated protein 1
Gene Alias	AFAP; AFAP110; AFAP-110
Transcripts	ENSG00000196526
Virus	HBV
Gene Type	protein coding
HPA Location Info	Actin filaments;Cytosol;Focal adhesion sites;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8N556
HGNC ID	HGNC:24017
VEGA ID	OTTHUMG00000125515
OMIM ID	608252
String ID	9606.ENSP00000410689
PharmGKB ID	PA162375733

Target gene [AFAP1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1017291	chr4	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of AFAP1 expression and immune infiltrating cell level correlation result in HBV+ samples
AFAP1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).