HBV Target gene Detail Information

> AFAP1 Gene Search Result


Gene Information
Gene Name AFAP1
Gene ID 60312
Gene Full Name actin filament associated protein 1
Gene Alias AFAP; AFAP110; AFAP-110
Transcripts ENSG00000196526
Virus HBV
Gene Type protein coding
HPA Location Info Actin filaments;Cytosol;Focal adhesion sites;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q8N556
HGNC ID HGNC:24017
VEGA ID OTTHUMG00000125515
OMIM ID 608252
String ID 9606.ENSP00000410689
PharmGKB ID PA162375733
Target gene [AFAP1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1017291 chr4 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of AFAP1 expression and immune infiltrating cell level correlation result in HBV+ samples
AFAP1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).