HBV Target gene Detail Information

> ADRA1D Gene Search Result

Gene Information

Gene Name	ADRA1D
Gene ID	146
Gene Full Name	adrenoceptor alpha 1D
Gene Alias	DAR; ADRA1; ADRA1A; ADRA1R; ALPHA1; dJ779E11.2
Transcripts	ENSG00000171873
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins
Uniport_ID	P25100
HGNC ID	HGNC:280
VEGA ID	OTTHUMG00000031779
OMIM ID	104219
String ID	9606.ENSP00000368766
Drugbank ID	BE0000715; BE0004888
PharmGKB ID	PA24597

Target gene [ADRA1D] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1013714	chr20	3	1		4	View
1403587	chr20	3	1		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ADRA1D expression and immune infiltrating cell level correlation result in HBV+ samples
ADRA1D expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).