HBV Target gene Detail Information

> ADRA1B Gene Search Result


Gene Information
Gene Name ADRA1B
Gene ID 147
Gene Full Name adrenoceptor alpha 1B
Gene Alias ADRA1; ALPHA1BAR
Transcripts ENSG00000170214
Virus HBV
Gene Type protein coding
HPA Location Info Plasma membrane;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID P35368
HGNC ID HGNC:278
VEGA ID OTTHUMG00000130327
OMIM ID 104220
String ID 9606.ENSP00000306662
Drugbank ID BE0000575; BE0004888
PharmGKB ID PA33
Target gene [ADRA1B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1017232 chr5 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ADRA1B expression and immune infiltrating cell level correlation result in HBV+ samples
ADRA1B expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).