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HBV Target gene Detail Information

> ADRA1A Gene Search Result


Gene Information
Gene Name ADRA1A
Gene ID 148
Gene Full Name adrenoceptor alpha 1A
Gene Alias ADRA1C; ADRA1L1; ALPHA1AAR
Transcripts ENSG00000120907
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;Vesicles;
Membrane Info Predicted membrane proteins
HPA Protein Class Info FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins
Uniport_ID P35348
HGNC ID HGNC:277
VEGA ID OTTHUMG00000099459
OMIM ID 104221
String ID 9606.ENSP00000369960
Drugbank ID BE0000501; BE0004888
PharmGKB ID PA34
Target gene [ADRA1A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1001339 chr8 171 247 413 831 View
1008876 chr8 13 5 1 19 View
1017450 chr8 1 1 View
1400081 chr8 35 35 View
1404459 chr8 1 2 3 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ADRA1A expression and immune infiltrating cell level correlation result in HBV+ samples
ADRA1A expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).