HPV Target gene Detail Information

> ADORA3 Gene Search Result

Gene Information

Gene Name	ADORA3
Gene ID	140
Gene Full Name	adenosine A3 receptor
Gene Alias	A3AR
Transcripts	ENSG00000282608
Virus	HPV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins
Uniport_ID	P0DMS8
HGNC ID	HGNC:268
VEGA ID	OTTHUMG00000011957
OMIM ID	600445
String ID	9606.ENSP00000358730
Drugbank ID	BE0000354
PharmGKB ID	PA24589

Target gene [ADORA3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5402033	chr1	99	280	198	577	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE65858 (GEO)	Head and neck squamous cell carcinoma	270	Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE65858
HeatMap of cell type fractions in all samples	Lollipop of ADORA3 expression and immune infiltrating cell level correlation result in HPV+ samples
ADORA3 expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of ADORA3 expression and immune infiltrating cell level correlation result in HPV+ samples
ADORA3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).