HBV Target gene Detail Information

> ADH1A Gene Search Result

Gene Information

Gene Name	ADH1A
Gene ID	124
Gene Full Name	alcohol dehydrogenase 1A (class I), alpha polypeptide
Gene Alias	ADH1
Transcripts	ENSG00000187758
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
HPA Protein Class Info	Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P07327
HGNC ID	HGNC:249
VEGA ID	OTTHUMG00000131026
OMIM ID	103700
String ID	9606.ENSP00000209668
Drugbank ID	BE0000227
PharmGKB ID	PA24570

Target gene [ADH1A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1017218	chr4		1		1	View
1019565	chr4				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ADH1A expression and immune infiltrating cell level correlation result in HBV+ samples
ADH1A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).