HIV Target gene Detail Information

> ADD3 Gene Search Result

Gene Information

Gene Name	ADD3
Gene ID	120
Gene Full Name	adducin 3
Gene Alias	ADDL; CPSQ3
Transcripts	ENSG00000148700
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q9UEY8
HGNC ID	HGNC:245
VEGA ID	OTTHUMG00000019032
OMIM ID	601568
String ID	9606.ENSP00000348381
PharmGKB ID	PA24567

Target gene [ADD3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006039	chr10	21	3	3	27	View
4013728	chr6	2		1	3	View
4014811	chr10	1	1		2	View
4016561	chr10				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ADD3 expression and immune infiltrating cell level correlation result in HIV+ samples
ADD3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ADD3 expression and immune infiltrating cell level correlation result in HIV+ samples
ADD3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).