HTLV1 Target gene Detail Information

> ADCY7 Gene Search Result


Gene Information
Gene Name ADCY7
Gene ID 113
Gene Full Name adenylate cyclase 7
Gene Alias AC7
Transcripts ENSG00000121281
Virus HTLV1
Gene Type protein coding
HPA Location Info Cytosol;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID P51828
HGNC ID HGNC:238
VEGA ID OTTHUMG00000133172
OMIM ID 600385
String ID 9606.ENSP00000378187
PharmGKB ID PA28
Target gene [ADCY7] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6001556 chr16 142 176 79 397 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of ADCY7 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ADCY7 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of ADCY7 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ADCY7 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of ADCY7 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ADCY7 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).