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EBV Target gene Detail Information

> ADCY10 Gene Search Result


Gene Information
Gene Name ADCY10
Gene ID 55811
Gene Full Name adenylate cyclase 10
Gene Alias SAC; HCA2; SACI; Sacy; hsAC; HEL-S-7a
Transcripts ENSG00000143199
Virus EBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q96PN6
HGNC ID HGNC:21285
VEGA ID OTTHUMG00000034573
OMIM ID 605205
String ID 9606.ENSP00000356825
PharmGKB ID PA162375618
Target gene [ADCY10] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
3000352 chr1 23 6 29 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE102203 (GEO) B-cell lymphoma 9 Plasmablastic lymphomas (EBV+)(6), Plasmablastic lymphomas (EBV-)(3)
GSE100458 (GEO) Burkitt lymphoma 14 Burkitt lyphoma cell line Akata(EBV+)(2),Burkitt lyphoma cell line Akata(EBV-)(2),Burkitt lyphoma cell line Awia(EBV+)(2),Burkitt lyphoma cell line Awia(EBV-)(2),Burkitt lyphoma cell line Eli(EBV+)(1),Burkitt lyphoma cell line Eli(EBV-)(1),Burkitt lyphoma cell line Mutu(EBV+)(2),Burkitt lyphoma cell line Mutu(EBV-)(2)
GSE42867 (GEO) Burkitt lymphoma 12 Burkitt lymphoma cell line Awia (EBV+)(12)
GSE45919 (GEO) Infectious mononucleosis 24 Infectious mononucleosis (IM)(EBV+)(3), Normal (9), Latent EBV (12)
GSE85599 (GEO) Infectious mononucleosis 17 Chronic active EBV infection (EBV+)(5), Acute infectious mononucleosis (EBV+)(6), Normal (6)
GSE58240 (GEO) Multiple sclerosis 32 Multiple sclerosis IFN-β treated (EBV+)(16), Multiple sclerosis untreated (EBV+)(16)
GSE12452 (GEO) Nasopharyngeal carcinoma 41 Nasopharyngeal carcinoma (EBV+)(31), Normal(10)

> Dataset: GSE102203

HeatMap of cell type fractions in all samples Lollipop of ADCY10 expression and immune infiltrating cell level correlation result in EBV+ samples
ADCY10 expression: Low -> High

> Dataset: GSE100458

HeatMap of cell type fractions in all samples Lollipop of ADCY10 expression and immune infiltrating cell level correlation result in EBV+ samples
ADCY10 expression: Low -> High

> Dataset: GSE42867

HeatMap of cell type fractions in all samples Lollipop of ADCY10 expression and immune infiltrating cell level correlation result in EBV+ samples
ADCY10 expression: Low -> High

> Dataset: GSE45919

HeatMap of cell type fractions in all samples Lollipop of ADCY10 expression and immune infiltrating cell level correlation result in EBV+ samples
ADCY10 expression: Low -> High

> Dataset: GSE85599

HeatMap of cell type fractions in all samples Lollipop of ADCY10 expression and immune infiltrating cell level correlation result in EBV+ samples
ADCY10 expression: Low -> High

> Dataset: GSE58240

HeatMap of cell type fractions in all samples Lollipop of ADCY10 expression and immune infiltrating cell level correlation result in EBV+ samples
ADCY10 expression: Low -> High

> Dataset: GSE12452

HeatMap of cell type fractions in all samples Lollipop of ADCY10 expression and immune infiltrating cell level correlation result in EBV+ samples
ADCY10 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).