HBV Target gene Detail Information

> ADCY1 Gene Search Result

Gene Information

Gene Name	ADCY1
Gene ID	107
Gene Full Name	adenylate cyclase 1
Gene Alias	AC1; DFNB44
Transcripts	ENSG00000164742
Virus	HBV
Gene Type	protein coding
HPA Location Info	Mitochondria;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q08828
HGNC ID	HGNC:232
VEGA ID	OTTHUMG00000155420
OMIM ID	103072
String ID	9606.ENSP00000297323
Drugbank ID	BE0000269
PharmGKB ID	PA24560

Target gene [ADCY1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1011959	chr7	7	1		8	View
1404800	chr7	26	36	95	157	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ADCY1 expression and immune infiltrating cell level correlation result in HBV+ samples
ADCY1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).