HIV Target gene Detail Information

> ADCK5 Gene Search Result

Gene Information

Gene Name	ADCK5
Gene ID	203054
Gene Full Name	aarF domain containing kinase 5
Transcripts	ENSG00000285451
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Predicted membrane proteins
Uniport_ID	Q3MIX3
HGNC ID	HGNC:21738
VEGA ID	OTTHUMG00000165190
String ID	9606.ENSP00000310547
PharmGKB ID	PA134963849

Target gene [ADCK5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000451	chr8	125	250	79	454	View
4005838	chr8	28	1		29	View
4006514	chr8	12	11	1	24	View
4009394	chr8	9	3		12	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ADCK5 expression and immune infiltrating cell level correlation result in HIV+ samples
ADCK5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).