HTLV1 Target gene Detail Information

> ADAT1 Gene Search Result

Gene Information

Gene Name	ADAT1
Gene ID	23536
Gene Full Name	adenosine deaminase, tRNA specific 1
Gene Alias	HADAT1
Transcripts	ENSG00000065457
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q9BUB4
HGNC ID	HGNC:228
VEGA ID	OTTHUMG00000137611
OMIM ID	604230
String ID	9606.ENSP00000310015
PharmGKB ID	PA24558

Target gene [ADAT1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6003886	chr16	27	106	4	137	View
6017734	chr16	10			10	View
6017735	chr16	10			10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of ADAT1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ADAT1 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of ADAT1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ADAT1 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of ADAT1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ADAT1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).