HBV Target gene Detail Information

> ADARB2 Gene Search Result


Gene Information
Gene Name ADARB2
Gene ID 105
Gene Full Name adenosine deaminase, RNA specific B2 (inactive)
Gene Alias RED2; ADAR3
Transcripts ENSG00000185736
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q9NS39
HGNC ID HGNC:227
VEGA ID OTTHUMG00000017543
OMIM ID 602065
String ID 9606.ENSP00000370713
PharmGKB ID PA24557
Target gene [ADARB2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1011900 chr10 7 1 8 View
1018157 chr10 0 View
1018158 chr10 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ADARB2 expression and immune infiltrating cell level correlation result in HBV+ samples
ADARB2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).