HIV Target gene Detail Information

> ADAR Gene Search Result

Gene Information

Gene Name	ADAR
Gene ID	103
Gene Full Name	adenosine deaminase, RNA specific
Gene Alias	DSH; AGS6; G1P1; IFI4; P136; ADAR1; DRADA; DSRAD; IFI-4; K88DSRBP
Transcripts	ENSG00000160710
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID	P55265
HGNC ID	HGNC:225
VEGA ID	OTTHUMG00000037261
OMIM ID	146920
String ID	9606.ENSP00000357459
PharmGKB ID	PA24555

Target gene [ADAR] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006518	chr1	21	3		24	View
4008122	chr1	16			16	View
4009637	chr1	10	1		11	View
4013550	chr1	3			3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ADAR expression and immune infiltrating cell level correlation result in HIV+ samples
ADAR expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ADAR expression and immune infiltrating cell level correlation result in HIV+ samples
ADAR expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).