HTLV1 Target gene Detail Information

> ADAP1 Gene Search Result

Gene Information

Gene Name	ADAP1
Gene ID	11033
Gene Full Name	ArfGAP with dual PH domains 1
Gene Alias	GCS1L; CENTA1; p42IP4
Transcripts	ENSG00000105963
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	O75689
HGNC ID	HGNC:16486
VEGA ID	OTTHUMG00000023380
OMIM ID	608114
String ID	9606.ENSP00000442682
PharmGKB ID	PA26404

Target gene [ADAP1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6003632	chr7	141	8		149	View
6003939	chr7	134	1		135	View
6020581	chr7	4		2	6	View
6020623	chr7	4		2	6	View
6020658	chr7	4		2	6	View
6020685	chr7	4		2	6	View
6020695	chr7	4		2	6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of ADAP1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ADAP1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).