HIV Target gene Detail Information

> ADAMTS18 Gene Search Result

Gene Information

Gene Name	ADAMTS18
Gene ID	170692
Gene Full Name	ADAM metallopeptidase with thrombospondin type 1 motif 18
Gene Alias	KNO2; MMCAT; ADAMTS21
Transcripts	ENSG00000140873
Virus	HIV
Gene Type	protein coding
HPA Location Info	Midbody;Mitotic spindle;Predicted to be secreted;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins
Gene Function	Suppressor gene
Uniport_ID	Q8TE60
HGNC ID	HGNC:17110
VEGA ID	OTTHUMG00000137619
OMIM ID	607512
String ID	9606.ENSP00000282849
PharmGKB ID	PA24544

Target gene [ADAMTS18] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4016499	chr16				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ADAMTS18 expression and immune infiltrating cell level correlation result in HIV+ samples
ADAMTS18 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).