HIV Target gene Detail Information

> ADAMTS18 Gene Search Result


Gene Information
Gene Name ADAMTS18
Gene ID 170692
Gene Full Name ADAM metallopeptidase with thrombospondin type 1 motif 18
Gene Alias KNO2; MMCAT; ADAMTS21
Transcripts ENSG00000140873
Virus HIV
Gene Type protein coding
HPA Location Info Midbody;Mitotic spindle;Predicted to be secreted;
HPA Protein Class Info Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins
Gene Function Suppressor gene
Uniport_ID Q8TE60
HGNC ID HGNC:17110
VEGA ID OTTHUMG00000137619
OMIM ID 607512
String ID 9606.ENSP00000282849
PharmGKB ID PA24544
Target gene [ADAMTS18] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4016499 chr16 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of ADAMTS18 expression and immune infiltrating cell level correlation result in HIV+ samples
ADAMTS18 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).