HBV Target gene Detail Information

> ADAMTS14 Gene Search Result


Gene Information
Gene Name ADAMTS14
Gene ID 140766
Gene Full Name ADAM metallopeptidase with thrombospondin type 1 motif 14
Transcripts ENSG00000138316
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Cancer-related genes, Plasma proteins, Predicted secreted proteins
Uniport_ID Q8WXS8
HGNC ID HGNC:14899
VEGA ID OTTHUMG00000018414
OMIM ID 607506
String ID 9606.ENSP00000362304
PharmGKB ID PA24540
Target gene [ADAMTS14] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1016735 chr10 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ADAMTS14 expression and immune infiltrating cell level correlation result in HBV+ samples
ADAMTS14 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).