HBV Target gene Detail Information

> ADAM9 Gene Search Result


Gene Information
Gene Name ADAM9
Gene ID 8754
Gene Full Name ADAM metallopeptidase domain 9
Gene Alias MCMP; MDC9; CORD9; Mltng
Transcripts ENSG00000282230
Virus HBV
Gene Type protein coding
HPA Location Info Vesicles;Endoplasmic reticulum;Predicted to be secreted;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins
Gene Function Oncogene
Uniport_ID Q13443
HGNC ID HGNC:216
VEGA ID OTTHUMG00000190616
OMIM ID 602713
String ID 9606.ENSP00000419446
Drugbank ID BE0003412
PharmGKB ID PA24534
Target gene [ADAM9] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005673 chr8 18 16 15 49 View
1012104 chr8 5 1 1 7 View
1401322 chr8 18 16 15 49 View
1402060 chr8 5 1 1 7 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ADAM9 expression and immune infiltrating cell level correlation result in HBV+ samples
ADAM9 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).