HIV Target gene Detail Information

> ADAM8 Gene Search Result

Gene Information

Gene Name	ADAM8
Gene ID	101
Gene Full Name	ADAM metallopeptidase domain 8
Gene Alias	MS2; CD156; CD156a
Transcripts	ENSG00000151651
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	P78325
HGNC ID	HGNC:215
VEGA ID	OTTHUMG00000019309
OMIM ID	602267
String ID	9606.ENSP00000453302
PharmGKB ID	PA24533

Target gene [ADAM8] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006860	chr10	7	8	7	22	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ADAM8 expression and immune infiltrating cell level correlation result in HIV+ samples
ADAM8 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ADAM8 expression and immune infiltrating cell level correlation result in HIV+ samples
ADAM8 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).