HIV Target gene Detail Information

> ADAM23 Gene Search Result

Gene Information

Gene Name	ADAM23
Gene ID	8745
Gene Full Name	ADAM metallopeptidase domain 23
Gene Alias	MDC3; MDC-3
Transcripts	ENSG00000114948
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	O75077
HGNC ID	HGNC:202
VEGA ID	OTTHUMG00000132919
OMIM ID	603710
String ID	9606.ENSP00000264377
PharmGKB ID	PA24519

Target gene [ADAM23] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4011737	chr2	6			6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ADAM23 expression and immune infiltrating cell level correlation result in HIV+ samples
ADAM23 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).