HBV Target gene Detail Information

> ADAM17 Gene Search Result


Gene Information
Gene Name ADAM17
Gene ID 6868
Gene Full Name ADAM metallopeptidase domain 17
Gene Alias CSVP; TACE; NISBD; ADAM18; CD156B; NISBD1
Transcripts ENSG00000151694
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;
Membrane Info Predicted membrane proteins
HPA Protein Class Info CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID P78536
HGNC ID HGNC:195
VEGA ID OTTHUMG00000090425
OMIM ID 603639
String ID 9606.ENSP00000309968
Drugbank ID BE0003754
PharmGKB ID PA24512
Target gene [ADAM17] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1008209 chr2 9 6 7 22 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ADAM17 expression and immune infiltrating cell level correlation result in HBV+ samples
ADAM17 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).