HIV Target gene Detail Information

> ACVR1C Gene Search Result

Gene Information

Gene Name	ACVR1C
Gene ID	130399
Gene Full Name	activin A receptor type 1C
Gene Alias	ALK7; ACVRLK7
Transcripts	ENSG00000123612
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Gene Function	Suppressor gene
Uniport_ID	Q8NER5
HGNC ID	HGNC:18123
VEGA ID	OTTHUMG00000131964
OMIM ID	608981
String ID	9606.ENSP00000243349
PharmGKB ID	PA134908988

Target gene [ACVR1C] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002464	chr2	49	38	6	93	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ACVR1C expression and immune infiltrating cell level correlation result in HIV+ samples
ACVR1C expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).