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HPV Target gene Detail Information

> ACTL7B Gene Search Result


Gene Information
Gene Name ACTL7B
Gene ID 10880
Gene Full Name actin like 7B
Gene Alias Tact1
Transcripts ENSG00000148156
Virus HPV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q9Y614
HGNC ID HGNC:162
VEGA ID OTTHUMG00000020462
OMIM ID 604304
String ID 9606.ENSP00000363799
PharmGKB ID PA24484
Target gene [ACTL7B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5000128 chr9 879 553 200 1632 View
5000179 chr9 606 113 63 782 View
5001026 chr9 54 4 58 View
5001626 chr9 16 7 4 27 View
5001821 chr9 20 2 22 View
5004722 chr9 0 View
5403461 chr9 129 2 131 View
5404540 chr9 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of ACTL7B expression and immune infiltrating cell level correlation result in HPV+ samples
ACTL7B expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of ACTL7B expression and immune infiltrating cell level correlation result in HPV+ samples
ACTL7B expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of ACTL7B expression and immune infiltrating cell level correlation result in HPV+ samples
ACTL7B expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of ACTL7B expression and immune infiltrating cell level correlation result in HPV+ samples
ACTL7B expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of ACTL7B expression and immune infiltrating cell level correlation result in HPV+ samples
ACTL7B expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of ACTL7B expression and immune infiltrating cell level correlation result in HPV+ samples
ACTL7B expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).