HPV Target gene Detail Information

> ACTL6A Gene Search Result


Gene Information
Gene Name ACTL6A
Gene ID 86
Gene Full Name actin like 6A
Gene Alias Arp4; ACTL6; BAF53A; INO80K; ARPN-BETA
Transcripts ENSG00000136518
Virus HPV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;
HPA Protein Class Info Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID O96019
HGNC ID HGNC:24124
VEGA ID OTTHUMG00000157782
OMIM ID 604958
String ID 9606.ENSP00000397552
PharmGKB ID PA134914203
Target gene [ACTL6A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5402547 chr3 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE40774 (GEO) Head and neck squamous cell carcinoma 134 Head and neck Squamous cell carcinomas GLOTTIC LARYNX (EBV-)(2), Head and neck Squamous cell carcinomas HYPOPHARYNX (EBV-)(9), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV-)(23), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV+)(2), Head and neck Squamous cell carcinomas OROPHARYNX (EBV-)(22), Head and neck Squamous cell carcinomas OROPHARYNX (EBV+)(54), Head and neck Squamous cell carcinomas OTHER (EBV+)(1), Head and neck Squamous cell carcinomas SUBGLOTTIC LARYNX (EBV-)(1), Head and neck Squamous cell carcinomas SUPRAGLOTTIC (EBV-)(19), Squamous cell carcinomas SUPRAGLOTTIC (EBV+)(1)
GSE138080 (GEO) Cervical intraepithelial neoplasia 25 Normal (10), Cervical intraepithelial neoplasia (HPV+)(15)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of ACTL6A expression and immune infiltrating cell level correlation result in HPV+ samples
ACTL6A expression: Low -> High

> Dataset: GSE40774

HeatMap of cell type fractions in all samples Lollipop of ACTL6A expression and immune infiltrating cell level correlation result in HPV+ samples
ACTL6A expression: Low -> High

> Dataset: GSE138080

HeatMap of cell type fractions in all samples Lollipop of ACTL6A expression and immune infiltrating cell level correlation result in HPV+ samples
ACTL6A expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of ACTL6A expression and immune infiltrating cell level correlation result in HPV+ samples
ACTL6A expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).