HBV Target gene Detail Information

> ACTG2 Gene Search Result


Gene Information
Gene Name ACTG2
Gene ID 72
Gene Full Name actin, gamma 2, smooth muscle, enteric
Gene Alias ACT; ACTE; VSCM; ACTA3; ACTL3; ACTSG
Transcripts ENSG00000163017
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID P63267
HGNC ID HGNC:145
VEGA ID OTTHUMG00000129813
OMIM ID 102545
String ID 9606.ENSP00000386857
PharmGKB ID PA24469
Target gene [ACTG2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1400074 chr2 3 1 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ACTG2 expression and immune infiltrating cell level correlation result in HBV+ samples
ACTG2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).