HBV Target gene Detail Information

> ACTA2 Gene Search Result

Gene Information

Gene Name	ACTA2
Gene ID	59
Gene Full Name	actin, alpha 2, smooth muscle, aorta
Gene Alias	ACTSA
Transcripts	ENSG00000107796
Virus	HBV
Gene Type	protein coding
HPA Location Info	Actin filaments;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P62736
HGNC ID	HGNC:130
VEGA ID	OTTHUMG00000018700
OMIM ID	102620
String ID	9606.ENSP00000402373
Drugbank ID	BE0005001; BE0005076
PharmGKB ID	PA24456

Target gene [ACTA2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1016267	chr10	1			1	View
1403528	chr10	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ACTA2 expression and immune infiltrating cell level correlation result in HBV+ samples
ACTA2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).