HBV Target gene Detail Information

> ACTA2 Gene Search Result


Gene Information
Gene Name ACTA2
Gene ID 59
Gene Full Name actin, alpha 2, smooth muscle, aorta
Gene Alias ACTSA
Transcripts ENSG00000107796
Virus HBV
Gene Type protein coding
HPA Location Info Actin filaments;
HPA Protein Class Info Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID P62736
HGNC ID HGNC:130
VEGA ID OTTHUMG00000018700
OMIM ID 102620
String ID 9606.ENSP00000402373
Drugbank ID BE0005001; BE0005076
PharmGKB ID PA24456
Target gene [ACTA2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1016267 chr10 1 1 View
1403528 chr10 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ACTA2 expression and immune infiltrating cell level correlation result in HBV+ samples
ACTA2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).