HBV Target gene Detail Information

> ACSL3 Gene Search Result

Gene Information

Gene Name	ACSL3
Gene ID	2181
Gene Full Name	acyl-CoA synthetase long chain family member 3
Gene Alias	ACS3; FACL3; LACS3; LACS 3; PRO2194
Transcripts	ENSG00000123983
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoli;Nucleoli rim;Lipid droplets;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	O95573
HGNC ID	HGNC:3570
VEGA ID	OTTHUMG00000133160
OMIM ID	602371
String ID	9606.ENSP00000350012
PharmGKB ID	PA27967

Target gene [ACSL3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001741	chr2	156	315	36	507	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ACSL3 expression and immune infiltrating cell level correlation result in HBV+ samples
ACSL3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).