HTLV1 Target gene Detail Information

> ACSBG1 Gene Search Result

Gene Information

Gene Name	ACSBG1
Gene ID	23205
Gene Full Name	acyl-CoA synthetase bubblegum family member 1
Gene Alias	BG; BG1; BGM; LPD; GR-LACS
Transcripts	ENSG00000103740
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Vesicles;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q96GR2
HGNC ID	HGNC:29567
VEGA ID	OTTHUMG00000143734
OMIM ID	614362
String ID	9606.ENSP00000258873
Drugbank ID	BE0004272
PharmGKB ID	PA142672648

Target gene [ACSBG1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6007727	chr15	52			52	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of ACSBG1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ACSBG1 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of ACSBG1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ACSBG1 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of ACSBG1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ACSBG1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).