HTLV1 Target gene Detail Information

> ACP5 Gene Search Result


Gene Information
Gene Name ACP5
Gene ID 54
Gene Full Name acid phosphatase 5, tartrate resistant
Gene Alias HPAP; TRAP; TRACP5a; TRACP5b; TrATPase
Transcripts ENSG00000102575
Virus HTLV1
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID P13686
HGNC ID HGNC:124
VEGA ID OTTHUMG00000182036
OMIM ID 171640
String ID 9606.ENSP00000468767
PharmGKB ID PA24448
Target gene [ACP5] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6001995 chr19 225 41 37 303 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of ACP5 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ACP5 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of ACP5 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ACP5 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of ACP5 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ACP5 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).