HBV Target gene Detail Information

> ACOX1 Gene Search Result


Gene Information
Gene Name ACOX1
Gene ID 51
Gene Full Name acyl-CoA oxidase 1
Gene Alias ACOX; SCOX; PALMCOX
Transcripts ENSG00000161533
Virus HBV
Gene Type protein coding
HPA Location Info Peroxisomes;Nucleoli;
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID Q15067
HGNC ID HGNC:119
VEGA ID OTTHUMG00000180027
OMIM ID 609751
String ID 9606.ENSP00000293217
Drugbank ID BE0004135
PharmGKB ID PA21
Target gene [ACOX1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1008770 chr17 19 19 View
1014719 chr17 1 2 3 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ACOX1 expression and immune infiltrating cell level correlation result in HBV+ samples
ACOX1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).