HBV Target gene Detail Information

> ACOT7 Gene Search Result


Gene Information
Gene Name ACOT7
Gene ID 11332
Gene Full Name acyl-CoA thioesterase 7
Gene Alias ACT; ACH1; BACH; LACH; LACH1; hBACH; CTE-II
Transcripts ENSG00000097021
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID O00154
HGNC ID HGNC:24157
VEGA ID OTTHUMG00000001295
OMIM ID 602587
String ID 9606.ENSP00000367086
PharmGKB ID PA142672655
Target gene [ACOT7] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004432 chr1 40 25 16 81 View
1403672 chr1 40 25 16 81 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of ACOT7 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
ACOT7 expression: Low -> High
Lollipop of ACOT7 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of ACOT7 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ACOT7 expression and immune infiltrating cell level correlation result in HBV+ samples
ACOT7 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).