HBV Target gene Detail Information

> ACOT7 Gene Search Result


Gene Information
Gene Name ACOT7
Gene ID 11332
Gene Full Name acyl-CoA thioesterase 7
Gene Alias ACT; ACH1; BACH; LACH; LACH1; hBACH; CTE-II
Transcripts ENSG00000097021
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID O00154
HGNC ID HGNC:24157
VEGA ID OTTHUMG00000001295
OMIM ID 602587
String ID 9606.ENSP00000367086
PharmGKB ID PA142672655
Target gene [ACOT7] related to VISs
DVIDChromosomeHMTFBSCASum of Overlapped RecordsDetail
1004432 chr1 40 25 16 81 View
1403672 chr1 40 25 16 81 View
Showing 1 to 2 of 2 entries
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Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of ACOT7 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
ACOT7 expression: Low -> High
Lollipop of ACOT7 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of ACOT7 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ACOT7 expression and immune infiltrating cell level correlation result in HBV+ samples
ACOT7 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).