HPV Target gene Detail Information

> ACOT11 Gene Search Result

Gene Information

Gene Name	ACOT11
Gene ID	26027
Gene Full Name	acyl-CoA thioesterase 11
Gene Alias	BFIT; THEA; THEM1; STARD14
Transcripts	ENSG00000162390
Virus	HPV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8WXI4
HGNC ID	HGNC:18156
VEGA ID	OTTHUMG00000009891
OMIM ID	606803
String ID	9606.ENSP00000360366
PharmGKB ID	PA38303

Target gene [ACOT11] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5400827	chr1	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE40774 (GEO)	Head and neck squamous cell carcinoma	134	Head and neck Squamous cell carcinomas GLOTTIC LARYNX (EBV-)(2), Head and neck Squamous cell carcinomas HYPOPHARYNX (EBV-)(9), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV-)(23), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV+)(2), Head and neck Squamous cell carcinomas OROPHARYNX (EBV-)(22), Head and neck Squamous cell carcinomas OROPHARYNX (EBV+)(54), Head and neck Squamous cell carcinomas OTHER (EBV+)(1), Head and neck Squamous cell carcinomas SUBGLOTTIC LARYNX (EBV-)(1), Head and neck Squamous cell carcinomas SUPRAGLOTTIC (EBV-)(19), Squamous cell carcinomas SUPRAGLOTTIC (EBV+)(1)
GSE138080 (GEO)	Cervical intraepithelial neoplasia	25	Normal (10), Cervical intraepithelial neoplasia (HPV+)(15)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE40774
HeatMap of cell type fractions in all samples	Lollipop of ACOT11 expression and immune infiltrating cell level correlation result in HPV+ samples
ACOT11 expression: Low -> High

> Dataset: GSE138080
HeatMap of cell type fractions in all samples	Lollipop of ACOT11 expression and immune infiltrating cell level correlation result in HPV+ samples
ACOT11 expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of ACOT11 expression and immune infiltrating cell level correlation result in HPV+ samples
ACOT11 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).